Open Access Te Herenga Waka-Victoria University of Wellington
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Microdosing Psychedelics for Cognitive Enhancement: A Naturalistic Exploration of User Experiences

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posted on 2025-09-24, 01:26 authored by Luke Pelham
<p><strong>Psychedelics have recently grown in scientific interest, among this, there have been promising findings regarding its potential to treat a range of health problems (such as depression, anxiety, PTSD). Despite the growing research interest in psychedelics, there is little research investigating the effects of microdoses: tiny doses that produce sub-hallucinogenic effects. Additionally, there is little research investigating the ability of psychedelics in improving cognitive functioning. Cognitive difficulties are becoming an increasing problem worldwide with deficits arising alongside a variety of internal and external factors (e.g., psychiatric disorders, neurological damage, and general aging). Our study addresses the limitations in current research by focusing specifically on cognitive functioning and its potential mediating effects. Our study investigated the effects of psychedelic microdosing on cognitive functioning and co-occurring factors that may be mediating these effects. We hypothesised that changes in cognition will be mediated by other factors common to the psychedelic experience such as changes in mood and lifestyle. A quantitative content analysis was performed of Reddit posts collected from the r/microdosing subreddit. An exploratory survey was also distributed to collect further insight that may have been missed from the Reddit data. Results from both data sources highlight that improvements in cognition are frequently reported following microdosing. In addition, both data sources highlight prominent improvements in other domains of microdosing such as mood, social, and lifestyle changes. The findings from this study suggest microdosing acts as a cognitive catalyst within a web of personal factors, challenging the standardised approach to psychedelic medicine in favour of a personalised therapeutic design.</strong></p>

History

Copyright Date

2025-09-24

Date of Award

2025-09-24

Publisher

Te Herenga Waka—Victoria University of Wellington

Rights License

Author Retains Copyright

Degree Discipline

Cognitive and Behavioural Neuroscience

Degree Grantor

Te Herenga Waka—Victoria University of Wellington

Degree Level

Masters

Degree Name

Master of Science

ANZSRC Socio-Economic Outcome code

280121 Expanding knowledge in psychology; 280112 Expanding knowledge in the health sciences

ANZSRC Type Of Activity code

1 Pure basic research

Victoria University of Wellington Item Type

Awarded Research Masters Thesis

Language

en_NZ

Victoria University of Wellington School

School of Psychology

Advisors

Ellenbroek, Bart; Youn, Jiun