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Preventing depression in final year secondary students: School-based randomized controlled trial

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posted on 2020-07-22, 01:36 authored by Y Perry, A Werner-Seidler, A Calear, A Mackinnon, C King, J Scott, S Merry, Theresa FlemingTheresa Fleming, K Stasiak, H Christensen, PJ Batterham
Background: Depression often emerges for the first time during adolescence. There is accumulating evidence that universal depression prevention programs may have the capacity to reduce the impact of depression when delivered in the school environment. Objective: This trial investigated the effectiveness of SPARX-R, a gamified online cognitive behavior therapy intervention for the prevention of depression relative to an attention-matched control intervention delivered to students prior to facing a significant stressor-final secondary school exams. It was hypothesized that delivering a prevention intervention in advance of a stressor would reduce depressive symptoms relative to the control group. Methods: A cluster randomized controlled trial was conducted in 10 government schools in Sydney, Australia. Participants were 540 final year secondary students (mean 16.7 [SD 0.51] years), and clusters at the school level were randomly allocated to SPARX-R or the control intervention. Interventions were delivered weekly in 7 modules, each taking approximately 20 to 30 minutes to complete. The primary outcome was symptoms of depression as measured by the Major Depression Inventory. Intention-to-treat analyses were performed. Results: Compared to controls, participants in the SPARX-R condition (n=242) showed significantly reduced depression symptoms relative to the control (n=298) at post-intervention (Cohen d=0.29) and 6 months post-baseline (d=0.21) but not at 18 months post-baseline (d=0.33). Conclusions: This is the first trial to demonstrate a preventive effect on depressive symptoms prior to a significant and universal stressor in adolescents. It demonstrates that an online intervention delivered in advance of a stressful experience can reduce the impact of such an event on the potential development or exacerbation of depression.

History

Preferred citation

Perry, Y., Werner-Seidler, A., Calear, A., Mackinnon, A., King, C., Clin, M., Scott, J., Merry, S., Fleming, T., Stasiak, K., Christensen, H. & Batterham, P.J. (2017). Preventing depression in final year secondary students: School-based randomized controlled trial. Journal of Medical Internet Research, 19(11), 1-11. https://doi.org/10.2196/jmir.8241

Journal title

Journal of Medical Internet Research

Volume

19

Issue

11

Publication date

2017-11-01

Pagination

1-11

Publisher

JMIR Publications Inc.

Publication status

Published

Contribution type

Article

Online publication date

2017-11-02

ISSN

1438-8871

eISSN

1438-8871

Article number

ARTN e369

Language

en