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Comparison of high protein and high fiber weight-loss diets in women with risk factors for the metabolic syndrome: A randomized trial
journal contributionposted on 20.08.2020, 05:30 by Lisa Te Morenga, MT Levers, SM Williams, RC Brown, J Mann
Background: Studies have suggested that moderately high protein diets may be more appropriate than conventional low-fat high carbohydrate diets for individuals at risk of developing the metabolic syndrome and type 2 diabetes. However in most such studies sources of dietary carbohydrate may not have been appropriate and protein intakes may have been excessively high. Thus, in a proof-of-concept study we compared two relatively low-fat weight loss diets - one high in protein and the other high in fiber-rich, minimally processed cereals and legumes - to determine whether a relatively high protein diet has the potential to confer greater benefits. Methods. Eighty-three overweight or obese women, 18-65 years, were randomized to either a moderately high protein (30% protein, 40% carbohydrate) diet (HP) or to a high fiber, relatively high carbohydrate (50% carbohydrate, > 35 g total dietary fiber, 20% protein) diet (HFib) for 8 weeks. Energy intakes were reduced by 2000 - 4000 kJ per day in order to achieve weight loss of between 0.5 and 1 kg per week. Results: Participants on both diets lost weight (HP: -4.5 kg [95% confidence interval (CI):-3.7, -5.4 kg] and HFib: -3.3 kg [95% CI: -4.2, -2.4 kg]), and reduced total body fat (HP: -4.0 kg [5% CI:-4.6, -3.4 kg] and HFib: -2.5 kg [95% CI: -3.5, -1.6 kg]), and waist circumference (HP: -5.4 cm [95% CI: -6.3, -4.5 cm] and HFib: -4.7 cm [95% CI: -5.8, -3.6 cm]), as well as total and LDL cholesterol, triglycerides, fasting plasma glucose and blood pressure. However participants on HP lost more body weight (-1.3 kg [95% CI: -2.5, -0.1 kg; p = 0.039]) and total body fat (-1.3 kg [95% CI: -2.4, -0.1; p = 0.029]). Diastolic blood pressure decreased more on HP (-3.7 mm Hg [95% CI: -6.2, -1.1; p = 0.005]). Conclusions: A realistic high protein weight-reducing diet was associated with greater fat loss and lower blood pressure when compared with a high carbohydrate, high fiber diet in high risk overweight and obese women. © 2011 Te Morenga et al; licensee BioMed Central Ltd.
Preferred citationTe Morenga, L. A., Levers, M. T., Williams, S. M., Brown, R. C. & Mann, J. (2011). Comparison of high protein and high fiber weight-loss diets in women with risk factors for the metabolic syndrome: A randomized trial. Nutrition Journal, 10(1), 40-. https://doi.org/10.1186/1475-2891-10-40
Journal titleNutrition Journal
PublisherSpringer Science and Business Media LLC
Online publication date28/04/2011
Read the peer-reviewed publication
ClinicalClinical Medicine and ScienceDiabetesClinical ResearchClinical Trials and Supportive ActivitiesObesityNutritionPreventionMetabolic and EndocrineCardiovascularAdolescentAdultAgedBlood GlucoseBlood PressureCholesterolDiabetes Mellitus, Type 2Diet, Fat-RestrictedDiet, ReducingDietary CarbohydratesDietary FiberDietary ProteinsEnergy IntakeFemaleHumansMetabolic SyndromeMiddle AgedRisk FactorsSingle-Blind MethodTriglyceridesWeight LossYoung AdultMetabolic Syndrome XNutrition & DieteticsNutrition and Dietetics